科研经验：
南京大学物理学院教授，
2010.5至今
University of British Columbia，化学系，博士后
2009.5-2010.4
科研项目：
国家自然科学基金面上项目：弹性蛋白力学构造的单分子研究 （2011-2013）；蛋白质折叠的单分子力谱研究（2012-2014）；新世纪人才支持计划（2011-2013）
代表作：
1.
“How Do Proteins
Unfold upon Adsorption on Nanoparticle Surfaces?”
Pan, H, Qin, M, Meng, W, Cao, Y*, Wang, W* (2012) Langmuir. [Epub ahead of print]
2.
“A versatile "multiple fishhooks"
approach for the study of ligand-receptor interactions using single molecule
atomic force microscopy.” Han, X, Qin, M,
Pan, H, Cao, Y*, Wang, W* (2012) Langmuir 28:10020-5.
3.
“Single-molecule
experiments reveal the flexibility of a Per-ARNT-Sim
domain and the kinetic partitioning in the unfolding pathway under
force” Gao X, Qin, M, Yin, PG, Liang, JY,
Wang, J, Cao, Y*, Wang, W* (2012) Biophysical Journal 102:2149-57.
4.
“Low folding
cooperativity of Hp35 revealed by single-molecule force spectroscopy
and molecular dynamics simulation” Lv, CM,
Tan, C, Qin, M., Zou, DW, Cao, Y*, Wang, W* (2012) Biophysical Journal 102:1944-51.
5.
“A genetically
encoded copper(I) sensor based on engineered structural distortion of
EGFP.” Liang, J, Qin, M, Xu,
R, Gao, X, Shen, Y, Xu, Q, Cao, Y*, Wang, W* (2012) Chemical Communications 48:3890-2
6.
“Designed
biomaterials to mimic the mechanical properties of muscles” Lv, S, Dudek, DM, Cao,
Y, Balamurali, MM, Gosline,
J, Li, HB (2010) Nature 465: 69-73
7.
“Single molecule
force spectroscopy reveals engineered metal chelation is a general
approach to enhance mechanical stability of proteins”
Cao, Y, Yoo, T,
Li, HB (2008) Proceedings of the National
Academy of Sciences USA 105:
11152-11157.
8.
“Engineered
elastomeric proteins with dual elasticity can be controlled by a
molecular regulator” Cao, Y, Li, HB
(2008) Nature Nanotechnology 3: 512-516.
9.
“A functional
single-molecule binding assay via force spectroscopy”
Cao, Y, Balamurali, MM,
Sharma, D, Li, HB (2007) Proceedings of the National
Academy of Sciences USA 104:15677-15681.
10.“Polyprotein
of GB1 is an ideal artificial elastomeric protein” Cao,
Y, Li, HB (2007) Nature Materials 6:
109-114.
